Dermalogica Phyto Nature E2 100ml
Description
Description
Exosome treatment with pumpkin enzyme for cell renewal
As skin ages, natural cell renewal slows significantly. While younger skin renews itself in about 28 days, this process can take up to 50 days or more later in life. The result is duller skin, uneven texture, buildup of dead skin cells, and reduced communication between skin cells—all factors that visibly accelerate the aging process.
Dermalogica Phyto Nature E² is an advanced daily leave-on treatment that specifically stimulates this cellular renewal. The formula combines two breakthrough technologies: plant-derived exosomes that enhance cell communication and pumpkin enzymes that gently exfoliate. Clinical studies show that natural skin regeneration is improved by 86%, for smoother, brighter, and visibly younger-looking skin.
Benefits
- Accelerates natural cell renewal with clinically proven 86% improvement
- Gently exfoliates without mechanical abrasion or harsh acids
- Reduces the appearance of fine lines and refines skin texture
- Evens skin tone and provides an immediate radiant result
- Protects against free radicals thanks to bio-fermented antioxidants
Active ingredients
Plant-derived exosomes (Lactococcus Ferment Lysate): Exosomes are microscopic vesicles that act as natural messengers between skin cells. This plant-based variant supports cell-to-cell communication and activates the skin's natural regeneration processes, for visible improvement of fine lines and skin quality.
Pumpkin Enzyme (Lactobacillus/Pumpkin Ferment Extract): A mild fruit enzyme that breaks the bonds between dead skin cells on the surface without stressing the skin barrier. It works gentler than glycolic acid or retinol and is therefore suitable for daily use—even for more sensitive skin types.
Curcuma Longa (Turmeric) Stem Cells & Acacia Senegal: Turmeric stem cells deliver powerful antioxidants and support the reduction of fine lines through their action in multiple skin layers. Acacia Senegal forms an invisible film that softens the skin and immediately improves visible smoothness.
Phyto Glycogen & Opuntia Ficus-Indica (Prickly Pear): This botanical combination enhances the skin's natural ability to exfoliate itself. Prickly pear extract is rich in antioxidants and flavonoids that hydrate the skin and help neutralize oxidative stress.
Bio-fermented Acetyl Glucosamine: A skin-identical ingredient that both hydrates and protects against free radicals. Clinical studies show that acetyl glucosamine reduces fine lines—especially around the eyes—and can help fade pigmentation spots with long-term use.
Lactic Acid: A mild AHA that supports the exfoliating action of the pumpkin enzymes. At the low concentration in this formula, it refines skin texture without irritation and helps the skin retain moisture better.
How to use
- Thoroughly cleanse the face with a suitable cleanser
- Apply Phyto Nature E² as the first step after cleansing, on slightly damp skin
- Distribute a few pumps evenly over face and neck
- Let it fully absorb before applying a serum or day cream
- Use morning and evening, always finish your morning routine with sun protection
Suitable for
- Mature skin with reduced cell renewal and dull complexion
- Skin with fine lines, uneven texture, or pigmentation spots
- Those looking for a mild alternative to retinol or glycolic acid
- Women aged 35 and older who want to build an advanced anti-aging routine
- Suitable for most skin types — do a patch test first if you have sensitive skin
Frequently Asked Questions
What are exosomes and why are they important in skincare?
Exosomes are small vesicles that cells use to send signals to each other. In skincare, plant-based exosomes support natural communication between skin cells, keeping regeneration processes more active. It is one of the most discussed innovations in scientific skincare.
Can I combine Phyto Nature E² with retinol or vitamin C?
Yes, if built up gradually. The formula is mild enough to be used alongside these actives. However, always introduce new actives gradually and watch your skin’s reaction. When using strong retinol simultaneously, we recommend using E² in the morning and retinol in the evening.
Is this product suitable for sensitive skin?
The pumpkin enzymes and low concentration of lactic acid make this formula milder than classic exfoliants with glycolic acid or salicylic acid. For sensitive or reactive skin, we do recommend doing a patch test first and gradually increasing use from a few times a week to daily use.

